前端編輯

管理員身份可於登入後,進行網站的前端管理。

 

郭柏麟 教授

 Prof. Po-Lin Kuo                                                       

 KUO

 

連絡電話:07-312-1101 ext. 2512#33

電子信箱:kuopolin@kmu.edu.tw

                  kuopolin@seed.net.tw

辦公位置:國研大樓四樓

學歷

分子細胞生物學、分子藥理學、天然物活性評估

經歷

·     高雄醫學大學臨床醫學研究所副教授

 

 

教授課程

高級分子及細胞生物學、儀器分析及實習、專題討論

 

代表著作

                                 


1.  Hsu YL, Hung JY, Chang WA, Jian SF, Lin YS, Pan YC, Wu CY, Kuo PL*. Hypoxic lung cancer-derived extracellular vesicle miR-103a increases the oncogenic effects of tumor associated macrophages by targeting PTEN. Molecular Therapy 2018 Feb 7;26(2):582-92.

2.   Hsu YL, Hung JY, Chang WA, Lin YS, Pan YC, Tsai PH, Wu CY, Kuo PL*. Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1. Oncogene 2017 Aug 24;36(34):4929-42.

3.   Liu KT, Liu YH, Liu HL, Chong IW, Yen MC*, Kuo PL*. Neutrophils are Essential in Short Hairpin RNA of Indoleamine 2,3- Dioxygenase Mediated-antitumor Efficiency. Molecular Therapy-Nucleic Acids 2016 Dec 6;5(12):e397.

4.  Hsu YL, Hung JY, Chou SH, Huang MS, Tsai MJ, Lin YS, Chiang SY, Ho YW, Wu CY, Kuo PL*. Angiomotin decreases lung cancer progression by sequestering oncogenic YAP/TAZ and decreasing Cyr61 expression. Oncogene 2015 Jul 30;34(31):4056-68.

5.   Kuo PL, Huang MS, Hung JY, Chou SH, Chiang SY, Huang YF, Yang CJ, Tsai MJ, Chang WA, Hsu YL*. Synergistic effect of lung tumor-associated dendritic cell-derived HB-EGF and CXCL5 on cancer progression. International Journal of Cancer 2014 Jul 1;135(1):96-108.

6.   Hsu, YL, Wu CY, Hung JY, Lin YS, Huang MS, Kuo PL*. Galectin-1 promotes lung cancer tumor metastasis by potentiating integrin α6β4 and Notch1/Jagged2 signaling pathway. Carcinogenesis 2013 Jun;34(6):1370-81.

7.   Kuo PL, Shen KH, Hung SH, Hsu YL*. CXCL1/GROα increases cell migration and invasion of prostate cancer by decreasing fibulin-1 expression through NF-κB/HDAC1 epigenetic regulation. Carcinogenesis 2012 Dec;33(12):2477-87.

8.  Kuo PL*, Huang MS, Cheng DE, Hung JY, Yang CJ, Chou SH. Lung cancer-derived galectin-1 enhances tumorigenic potentiation of tumor associated dendritic cells by expressing HB-EGF. Journal of Biological Chemistry 2012 Mar 23;287(13):9753-64.

9.Hsu YL, Huang MS, Yang CJ, Hung JY, Wu LY, Kuo PL*. Lung tumor associated osteoblast-derived bone morphogenetic protein-2 increased epithelial-to-mesenchymal transition of cancer by Runx2/Snail signaling pathway. Journal of Biological Chemistry 2011 Oct 28;286(43):37335-46.

10.  Hsu YL, Huang MS, Cheng DE, Hung JY, Yang CJ, Chou SH, Kuo PL*. Lung tumor associated dendritic cell-derived amphiregulin increased cancer progression. Journal of Immunology 2011 Aug 15;187(4):1733-44.

11.  Kuo PL, Hung JY, Huang SK, Chou SH, Cheng DE, Jong YJ, Hung CH, Yang CJ, Tsai YM, Hsu YL*, Huang MS*. Lung cancer-derived galectin-1 mediates dendritic cell anergy through inhibitor of DNA binding 3/IL-10 signaling pathway. Journal of Immunology 2011 Feb 1;186(3):1521-30.

 

12.  Hsu YL, Hung JY, Ko YC, Hung CH, Huang MS*, Kuo PL*. Phospholipase D signaling pathway is involved in lung cancer-derived IL-8 increased osteoclastogenesis. Carcinogenesis 2010 Apr;31(4):587-96.

 

 

 

 

 

 

Go to top