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陳百薰教授    

連絡電話:07-312-1101 ext. 7233

電子信箱: d670014@kmu.edu.tw

辦公位置:高醫附設醫院啟川大樓11樓檢驗醫學部

專長

毒物檢驗檢驗醫學小兒內分泌  一般小兒科

研究領域

以質譜儀檢測藥物及毒物

學歷

高雄醫學大學醫學系

美國病理醫師學院 會士(fellow)

工作經歷

高雄醫學大學

醫學院臨床醫學研究所

教授

高雄醫學大學

醫學系實驗診斷學 小兒科學

教授 副教授 講師

高雄醫學大學附設醫院檢驗醫學部 兒科部

主治醫師

美國阿肯色州立大學醫學中心 病理部

臨床病理科住院醫師

高雄醫學大學附設醫院 小兒科

總住院醫師 住院醫師

 

教授課程:

  高級毒理學特論 毒理學特論

  高級器官毒理學特論 器官毒理學特論

  實驗診斷學特論

  檢驗醫學

  小兒科學

 

歷年在校行政服務

高醫大實驗診斷學主任

       環境醫學頂尖研究中心績效組組長

       環境醫學研究中心副主任

高醫大附設醫院檢驗醫學部主任

               臨床醫學研究部藥理毒理研究室主任

               毒物室主任

               門診及急診檢驗室主任

歷年獲得研究計畫經費補助(近五年)

NO 計畫名稱 核定經費 補助單位 計畫編號 起迄日期
1 平台3-2、新興環境污染物分析
 
700,000 頂尖計畫(高醫) KMU-TP105A19 105/11/01
106/10/31
2 平台3、新興環境污染物分析平台
 
1,163,000 頂尖計畫(高醫) KMU-TP104A21 104/10/01
105/09/30
3 平台4、藥物與毒物分析平台
 
450,000 頂尖計畫(高醫) KMU-TP104A22 104/10/01
105/09/30
4 平台三:新興環境汙染物體分析平台
 
600,000 頂尖計畫(高醫) KMU-TP103A28 103/08/01
104/07/31
5 102年度「特定族群之尿液監測調查研究」委託研究計畫
 
740,000 衛福部 DOH102-FDA-71007 102/02/22
102/12/31
6 探討葡萄催芽劑-氯乙醇(Chlorohydrin)於動物體內之毒性反應及調查中台灣地區常見農藥中毒之流行病學分析
 
500,000 高醫-彰基合作計畫 100-CCH-KMU-006 100/08/01
101/10/31

期刊論文發表(近五年)

  1. Lin CC, Yang CY, Shih YL, Huang YY, Yang TH, Liang JY, Chang CF, Hsieh LC, Chen BH, Huang YL* Persistence and titer changes of rubella antibodies in primiparous women who had been vaccinated with RA 27/3 at junior high school age. Clini Vacci Immunol 2012;19: 1-4
  2. Lee CH, Lee KW, Fang FM, Wu DC, Tsai SM, Chen PH, Shieh TY, Chen CH, Wu IC, Huang HL, Chen BH, Chang CH, Chen MK, Chou SH, Tsai YS, Chiang SL, Ko YC*. The neoplastic impact of tobacco-free betel-quid on the histological type and the anatomical site of aerodigestive tract cancers. Intern J Canc 2012;131: E733-43
  3. Wu, MT , Wu, CF, Wu JR, Chen, BH, Chen EK, Chao MC , Liu CK , Ho, CK* .The public health threat of phthalate-tainted foodstuffs in Taiwan: The policies the government implemented and the lessons we learned. Envir Intern 2012;44:0-75-9
  4. Liu CC, Wu CF, Shiea J, Cho YT, Hsieh TJ, Chou YH, Chen BH, Huang SP, Wu WJ, Shen JT, Chang MY, Huang CH, Chang AW, Wu MT*. Detection of melamine in a human renal uric acid stone by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Clin Chim Acta. 2012;413:19-20-1689-1698.
  5. Wu CF, Chen BH, Shiea J, Chen EK, Liu CK, Chao MC, Ho CK, Wu JR, Wu MT* Temporal changes of urinary oxidative metabolites of di(2-ethylhexyl)phthalate after the 2011 phthalate incident in Taiwanese children-Findings of a 6-month follow-up. Envir Sci Techn 2013;47: 3754-62
  6. Lin YT , Tsai MT , Chen YL, Cheng CM, Huang CC, Wu CF, Liu CC, Hsieh TJ, Shiea J, Chen BH, Wu MT* Can melamine levels in one-spot overnight urine specimen predict the total previous 24-hours melamine excretion in school children?. Clin Chim Acta 2013;420: 128-33.
  7. Wu CF, Hsieh TJ, Chen BH, Liu CC, Wu MT* A crossover study of noodle soup consumption in melamine bowls and total melamine excretion in urine. Arch Int Med 2013;173: 317-9.
  8. Wu MT, Wu CF, Chen BH, Chen EK, Chen YL, Shiea J, Lee WT, Chao MC, Wu JR. Intake of phthalate-tainted foods alters thyroid functions in Taiwanese children. PLOS ONE 2013;8:1-e55005(1-9).
  9. Lee HH, Lee JF, Lin SY, Lin YY, Wu CF, Wu MT, Chen BH* Simultaneous quantification of urine flunitrazepam, nimetazepam and nitrazepam by using liquid chromatography tandem mass spectrometry. Clin Chim Acta 2013;420:--134-139.
  10. Chen BH* Reliability of reagent strips for the measurement of glucosuria in a neonatal intensive care setting. Pediatrics Neonat 2014;55:6-424-5.
  11. Chen LM, Chen YC, Hsiao HP, Chen BH, Chao MC*. Role of thyrotropin-releasing hormone test in re-evaluation of congenital hypothyroidism. Kaohsiung J Med Sci. 2014 2014;30:8-383389.
  12. Wu CF, Chang-Chien GP, Su SW, Chen BH, Wu MT* Findings of 2,731 suspected phthalate-tainted foodstuffs during the 2011 phthalate incident in Taiwan. J Formos Med Assoc 2014;113:(9)-600-5.
  13. Lin CC, Huang HH, Hu CW, Chen BH, Chong IW, Chao YY, Huang YL Trace elements, oxidative stress and glycemic control in young people with type 1 diabetes mellitus. J Trac Elem in Medic Biol 2014;28: 18-22.
  14. Wu CF, Peng CY, Liu CC, Lin WY, Pan CH, Cheng CM, Hsieh HM, Hsieh TJ, Chen BH, Wu MT* Ambient melamine exposure and urinary biomarkers of early renal injury. J Am S Nephro 2015;26:11-2821-9.
  15. Hou JW, Lin CL, Tsai YA, Chang CH, Liao KW, Yu CJ, Yang W, Lee MJ, Huang PC, Sun CW, Wang YH, Lin FR, Wu WC, Lee MC, Pan WH, Chen BH, Wu MT, Chen CC, Wang SL, Lee CC, Hsiung CA, Chen ML. The effects of phthalate and nonylphenol exposure on body size and secondary sexual characteristics during puberty. Intern J Hygin Environ Heal. 2015 ;218: 603-15.
  16. Wu MT*, Wu CF, Chen BH. Behavioral intervention and decreased daily melamine exposure from melamine tableware. Environm Sci Techno 2015;49: 9964-70.
  17. Lee HH, Chen LY,Wang HL,Chen BH* Quantification of salivary arecoline, arecaidine and N-methylnipecotic acid levels in volunteers by liquid chromatography-tandem mass spectrometry. J Analy Toxicol 2015;39: 714-9.
  18. Kuo FC, Su SW, Wu CF, Huang MC, Shiea J, Chen BH, Chen YL, Wu MT* Relationship of urinary phthalate metabolites with serum thyroid hormones in pregnant women and their newborns: a prospective birth cohort in Taiwan. PLoS One 2015;10: 6-e0123884(1-15).
  19. Lee SL, Lo FS, Lee YJ, Chen BH, Wang RH. Predictors of glycemic control in adolescents of various age groups with type 1 diabetes. J Nursi Rese 2015;23: 271-9.
  20. Tsai HJ(equal contribution), Chen BH(equal contribution), Wu CF, Wang SL, Huang PC, Tsai YC, Chen ML, Ho CK, Hsiung CA, Wu MT Intake of phthalate-tainted foods and microalbuminuria in children: The 2011 Taiwan food scandal. Environ Int. 2016;89: 4-129-37.
  21. Chen CC, Wang SL, Wu MT, Wang YH, Huang PC, Chen BH, Sun CW, Ho CK, Shih YC, Shiu MN, Pan WH, Chen ML, Lee CC, Hsiung CA. Exposure estimation for risk assessment of the phthalate incident in Taiwan. PLoS One. 2016;11:3-e0151070.
  22. Lee CW, Su H, Chen PY, Lin SJ, Shiea J, Shin SJ, Chen BH* Rapid identification of pesticides in human oral fluid for emergency management by thermal desorption electrospray ionization/mass spectrometry. J Mass Spectro 2016;51: 97-104.
  23. Lo F S, Hsu H Y, Chen B H, Lee Y J, Chen Y T, Wang R H. Factors affecting health adaptation of Chinese adolescents with type 1 diabetes: A path model testing. J Child Heal Care 2016;20:-5-16.
  24. Lee HH, Lee JF, Lin SYChen BH* Simultaneous identification of abused drugs, benzodiazepines, and new psychoactive substances in urine by liquid chromatography tandem mass spectrometry. Kaohsiung J Med Sci 2016;32:118-27.
  25. Lee CW, Su H, Wu KD, Shiea J*, Wu DC, Chen BH*, Shin SJ. Rapid point-of-care identification of oral medications in gastric lavage content by ambient mass spectrometry in the emergency room. Rapid Commun Mass Spectrom. 2016 Jun 15;30(11):1295-303. 
  26. Tsai YA, Lin CL, Hou JW, Huang PC, Lee MC, Chen BH, Wu MT, Chen CC, Wang SL, Lee CC, Hsiung CA, Chen ML; RAPIT Group. Effects of high di(2-ethylhexyl) phthalate (DEHP) exposure due to tainted food intake on pre-pubertal growth characteristics in a Taiwanese population. Environ Res. 2016 Aug;149:197-205. 
  27. Lin CC, Tsweng GJ, Lee CF, Chen BH, Huang YL. Magnesium, zinc, and chromium levels in children, adolescents, and young adults with type 1 diabetes. Clin Nutr 2016 Aug;35(4):880-4.
  28. Tsai HJ, Wu CF, Tsai YC, Huang PC, Chen ML, Wang SL, Chen BH, Chen CC, Wu WC, Hsu PS, Hsiung CA, Wu MT.Intake of phthalate-tainted foods and serum thyroid hormones in Taiwanese children and adolescents. Sci Rep. 2016 Jul 29;6:30589. 
  29. Chen CY, Lo FS, Chen BH, Lu MH, Hsin YM, Wang RH. Pathways of emotional autonomy, self-care behaviors, and depressive symptoms on health adaptation in adolescents with type 1 diabetes. Nurs Outlook. 2016 Aug 19. 16:30169-5. 
  30. Liang WC, Lin YF, Liu TY, Chang SC, Chen BH, Nishino I, Jong YJ. Neurite growth could be impaired by ETFDH mutation but restored by mitochondrial cofactors. Muscle Nerve. 2016 Dec 9. doi: 10.1002/mus.25501.
  31. Chen CY, Lo FS, Chen BH, Lu MH, Hsin YM, Wang RH. Pathways of emotional autonomy, self-care behaviors, and depressive symptoms on health adaptation in adolescents with type 1 diabetes.Nurs Outlook. 2017 Jan - Feb;65(1):68-76. 
  32. Huang PC, Tsai CH, Chen CC, Wu MT, Chen ML, Wang SL, Chen BHLee CC, Jaakkola JJK, Wu WC, Chen MK, Hsiung CA, Group R. Intellectual evaluation of children exposed to phthalate-tainted products after the 2011 Taiwan phthalate episode. Environ Res. 2017 Mar 27;156:158-166.
  33. Chen CC, Wang YH, Wang SL, Huang PC, Chuang SC, Chen MH, Chen BH, Sun CW, Fu HC, Lee CC, Wu MT, Chen ML, Hsiung CA. Exposure sources and  their relative contributions to urinary phthalate metabolites among children in Taiwan. Int J Hyg Environ Health. 2017 Apr 22. pii: S1438-4639(17)30013-5. 
  34. Lin HY, HH LEE, JF Lee, BH Chen*: Urine specimen validity test for drug abuse testing in workplace and court settings. J Food Drug Analysis (accepted)

研討會論文發表(近五年)

1.      陳百薰*,  林心榆,  李慧華李忠峰林彥吟趙美琴 The studies of urine specimen validity test for drug test in two youth correction facilities in southern Taiwan. 台灣兒科醫學會第214屆學術演講會1020427-28台北市

2.      陳百薰*,  林心榆,  李慧華李忠峰林彥吟趙美琴URINE SPECIMEN VALIDITY TEST FOR DRUG ABUSE TEST FROM TWO JUNIOR DETENTION CENTERS IN SOUTHERN TAIWAN-THREE YEARS EXPERIENCE The 27th Congress of The International Pediatric Association 1020824-29. Australia Melbourne.

3.      李慧華,陳荔瑤,李忠峰,林心榆,林彥吟,王惠亮,陳百薰* Salivary Arecoline, Arecaidine and N-methylnipecotic Acid Levels During Areca Nut Chewing in Human Volunteers by Liquid Chromatography Tandem Mass Spectrometry第四屆亞洲與大洋洲質譜會議暨第十屆台灣質譜年會 1020710-12. 台北市

4.      劉家駒,吳佳芳,謝建台,周以和,陳百薰,黃書彬,吳文正,黃俊雄,張艾文,吳明蒼Detection of Melamine in an Adult Renal Uric Acid Stone by Matrix-Assisted Laser Desorption / Ionization Time-Of-Flight Mass Spectrometry (MALDI-TOF MS) 台灣泌尿科醫學會102年會暨第35次學術演講會1020831-0901高雄市義大醫院

5.      陳百薰* Clinical application of liquid chromatography tandem mass spectrometry 2013上海醫學檢驗醫學會年會醫學檢驗醫學會年會1021108 上海市

6.      李慧華,許筑婷,李忠峯,林心榆,楊淵傑,陳百薰*Quantification of Imatinib in Plasma by Using Liquid Chromatography Tandem Mass Spectrometry第十一屆台灣質譜學會年會暨學術研討會1030629-0701 台中市

7.      陳百薰* Current status of HTLV-1 infection in Taiwan. Japan Society of HTLV and Association Disease Annual Meeting. 1030822-24  日本東京

8.      劉家駒,吳佳芳,謝建台,周以和陳百薰黃書彬吳文正,黃俊雄,張艾文,吳明蒼利用基質輔助雷射脫附游離飛行時間質譜儀(MALDI-TOF MS)於臨床上提升含三聚氰胺尿路鈣結石之偵測率台灣泌尿科學醫學會年會暨第36次學術演講會 1030906 -07台北市

9.      李慧華許筑婷李忠峰林心榆江建華陳百薰* Quantification of Everolimus in Whole Blood by Using Liquid Chromatography Tandem Mass Spectrometry. 第十二屆台灣質譜學會年會1040713-15 新竹市

10.  陳百薰* Clinical toxicology application of liquid chromatography tandem mass spectrometry東方檢驗醫學會年會1041210-12上海市

11.  李慧華,  陳舜志李忠峰林心榆陳百薰* Simultaneously Drug Quantification in the Urine of Sexual Assault Victim by Using Liquid Chromatography Tandem Mass Spectrometry亞太臨床病理檢驗醫學會議1050325-27台北市

12.  李慧華陳舜志李忠峰林心榆陳百薰* Simultaneously Drug Quantification in the Urine of Sexual Assault Victim by Using Liquid Chromatography Tandem Mass Spectrometry13屆台灣質譜學會年會及2016年學術研討會1050627-29高雄市

13.  陳百薰藥物濫用之快速診斷第一屆快篩技術及應用研討會 1060324高雄市

14.  陳百薰* Rapid diagnosis of drug abuse第一屆長城檢驗醫學研討會1060407-09 北京市

15.  陳彥君,郭昶宏,蔡英明,林宜靜,蕭惠彬,陳百薰,陳怡婷,王詩綾,洪志興* The Suppressive Effects of Metformin on Th1-Related Chemokines Expression in Monocytes台灣兒科醫學會第230屆學術演講會1060422台北市

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